research funding


Since 2002 we have been investigating the field of NCL research. We want to understand what causes this fatal disease. Our ambitious aim is to develop a therapy in order to be able to cure NCL. Therefore, the € 50,000 NCL research award is awarded each year to projects that contribute to curing NCL. Furthermore we fund scholarships with our donations. Worldwide we are the biggest single sponsor in this area. To react quickly to new developments, we also offer short-term start-up support. These short projects can be extended to larger ones where appropriate. And because there are many overlaps between childhood and adult dementia, the Neurodegeneration Award was initiated this year.

 

To recieve the latest news and information about NCL research regularly, feel free to sign up for our Research Newsletter. For questions on the subjects of research and development or funding please contact Dr. Herman van der Putten.

Doctoral fellowships

Postgraduate and research scholarships are awarded for up to three years. Regular reports and visits to laboratories are part of the programme. Candidates for funding can be recommended by their supervisors followed by an interview with our research leader. Here, two of them present their projects: 

Heart problems are a typical accompanying disease of NCL. In her research project, Emily is investigating cardiac muscle cells which host the NCL defect to find out their functionality.


Supervisor: Dr. Katja Rietdorf, The Open University, Milton Keynes

Funding Partner: Batten Research Fonds, Bijou Brigitte Stiftung, Böttcher-Stiftung, NCL-Golf-Trophy, RT4 golf tournament, Stichting Beat Batten

Doctoral student Emily Coode
Doctoral student Emily Coode

Gemma has successfully used the CRISPR/Cas method to produce hiPS cells with CLN3 mutations, which are similar to patients' cells but have the same genetic background. These cells form the basis for her studies and, have become important tools for other laboratories to test potential drugs.

 

Supervisor: Prof. Dr. Hans Schöler, Max Planck Institut Münster

Funding Partners: Batten Research Fonds,  Berti Vogts, Münster Krimi Cup

Gemma Gomez Giro researches on NCL
Gemma Gomez Giro researches on NCL

Application procedure & steps

  1. first contact our research leader Dr. Herman van der Putten or call +49 (163) 738 3083 to make sure the project is in line with our goals
  2. submit a letter of intent (see download below) to present the project briefly 
  3. based on this we will decide whether to ask you to submit a full proposal. Full proposals will be examined by the board, the scientific advisory board and other external reviewers of the NCL Foundation.
Download
application form phd fellowship
ncl_application_form_phd_fellowship.doc
Microsoft Word Dokument 208.0 KB

Deadline: 28th February and 31st August every year


NCL research award

Clinical-orientated projects are particularly prizeworthyThe prize money is used to fund postdoctoral fellows, to implement the submitted project and to promote young scientists. In order to find a cure for jNCL, scientists from all over the world are encouraged to submit their projects, especially those from related fields like Alzheimer's, ageing and lysosomal storage diseases. The last two awardees in brief:

Dr. Thomas Wishart and his PhD student Maica Llavero Hurtado (University of Edinburgh) were the winners of this year’s NCL research award. The objective of their research project is to identify new approaches for an effective NCL therapy with the help of the €50,000 prize money. Since there are indications that communications between NCL patients’ neurons are faulty, the team is focusing on neurons’ control centres, the synapses.

 

Funding Partner: ADM Hamburg AG, Online-Campaign "Save the Brain", HanseMerkur Recognition Award for Child Protection, Münster Krimi Cup

Handover of the NCL Research Award
Handover of the NCL Research Award

The 6th NCL research award went to Dr. Christian Michael Grimm (Pharmacy Department, LMU Munich). Dr. Grimm and his team are developing new methods to investigate the role of membrane proteins - like the NCL protein CLN3 - in the lysosome and to identify therapeutic substances, which can compensate the loss of CLN3.

 

Funding Partner: IMS Health GmbH & Co. OHG, Lieselotte-Paulsen-Stiftung, Online-Campaign "Childhood memories“, United Charity

The 6th NCL Research Award went to Dr. Grimm
The 6th NCL Research Award went to Dr. Grimm

Application procedure & steps

  1. first contact our research leader Dr. Herman van der Putten or call +49 (163) 738 3083 to make sure the project is in line with our goals
  2. submit a letter of intent to present the project briefly 
  3. based on this we will decide whether to ask you to submit a full proposal. Full proposals will be sent out for peer review to at least two reviewers. We welcome recommendations for independent expert reviewer candidates, as well as proposals for exclusion due to potential conflict of interest.
Download
Letter of Intent
Letter-of-Intent (Application Form_2018)
Microsoft Word Dokument 297.0 KB
Download
NCL research award application form 2018
NCL_Research_Award (Application_Form_201
Microsoft Word Dokument 325.5 KB

Deadline: 30th November 2018


Neurodegeneration Award

Thanks to the great support of  the Joachim Herz Stiftung,  we are able to announce another €100,000 grant. The so-called Neurodegeneration Award 2018 covers a postdoctoral fellowship salary for two years. The aim is to foster and improve synergies in resarch into NCL childhood dementia and age-related neurodegeneration. Therefore, applicants must meet the following requirements:

  1. Two collaborating partners must co-apply 
  2. One partner must actively engage in CLN3 research
  3. The other must be engaged in research on age-related neuro-degeneration

Ideally, postdoctoral candidates should conduct a considerable part of their work in both laboratories. Interested laboratories first send us a brief letter of intent (see download above). After acceptance you will be asked to send in a full proposal. Send the application form to research@ncl-foundation.com. If you need help to find a collaborating partner do not hesitate to contact us. 

Download
NCL neurodegeneration award application form 2018
ncl_neurodegenerationresearchaward_appli
Microsoft Word Dokument 277.5 KB

Deadline: 28th February 2018


Short Projects

Funding proposals can also be requested for smaller projects. These projects shoud consist of research intended for practical application intended to form the basis of new projects.

NCL locations worldwide
NCL locations worldwide